Point of order.
"The beginning of wisdom is to call things by their proper name." - Confucius
When we take a GM long pickup frame, and bolt a passenger body onto it, it becomes a Suburban. Not a single thing wrong with that, but it can no longer be called a pickup truck.
The op asked about Dangerous Game rifles. Now there are Plains Game rifles, mountain rifles, beanfield and sendero rifles, varmint rifles and on and on.
If the discussion is a one gun for everything with a 3-12x40 scope, it's the 375 H&H that's the reigning champion. I personally think the better term for this is a "Heavy Game" rifle.
The larger 404, 416, 458, etc. with a red dot or 1-6 scope are what enters my mind when I hear "Dangerous Game" rifle. I'm a 416 and 450 Rigby fan.
This is my opinion, and it's worth exactly what you paid for it, but the 500NE, 500 Jeff, 505 and larger are "Stopping Rifles". I need one like I need a hole in the foot, but if Krish comes up with another CZ550 in 505 Gibbs, my bank account is just going to have to take a hit.
I'll call it a stopping rifle mostly because I need to stop buying rifles.