I have 2 rifles in this caliber. With my model 70, I have taken pronghorns, whitetails, mule deer, elk and black bears. Over the years I have worked up loads with Nosler Partitions in 150, 165 and 200 gr weights. In that rifle, 150s actually shot the best and I have killed many deer and pronghorns with that bullet. In the early 90s, I became a big fan of Barnes X bullets and I have been using those on game ever since. A few years ago, I purchased a NIB Remington model 700 Classic in 300 H&H and it sat in my gun room, waiting for just the right time to take it on a hunt. In April, I took it to the Eastern Cape on my first African hunt. With Barnes 180 grain TTSX bullets, It performed flawlessly on gemsbok, nyala, kudu, impala, waterbuck, zebra and and sable. All were one and done with no tracking required, but I did shoot the sable twice, as the first shot was a bit forward, breaking both shoulders but just clipping the lungs. The second shot was only take to hasten his demise. When I go back to Africa, I will likely take the same rifle for with my sights set on both colors of wildebeest, a black impala, a bushbuck a warthog and a ???.