It’s a minor but valid variable, tanks. As is the balance of the gun, and even the weight or simply the flexibility of the recoil pad. Putting them all together, it’s “stacking tolerances”. One of the first things a good load developer will tell you if they are loading for your double, or if they are re-regulating the wedge, is that your shooting of the gun may not reproduce their results. This could be by your size, how tightly you hold the gun, how much you honor or fight muzzle rise, etc.
They are an art, not a science. Hence, CNC cannot solve the regulation by throwing math at the problems of regulation.