It would be slow for elk probably. You are often taking longer shots and the accuracy would also suffer so it's not really a good elk round in open country. .300 is a much better choice or 7mm variations imo.
True, IF you are likely to shoot 400 yards or more, the wind drift would be a significant factor. I agree with @Wyatt Smith that for anything within 300 it would be excellent.
Yeah, if you get that speed would work fine, if you can shoot it. But it's still not a preferred caliber for elk imo.
Yeah, I didn't realize you would get that much speed so that is okay. But it's easier to shoot other calibers accurately not to mention weight, recoil, cost, etc. I live in Colorado and I don't recall anybody ever using one. Lots of .30.06 (not my recommendation either for elk), .300, 7mm and lots are going to the rds I hate for elk, 6.5CM and stuff like that.
You make a very good point.
I thought I'd never find something I loved as much as my .338 Win Mag......until the .375 Ruger landed in my hands. 329gr Hammer Hunters gives you reach. 2700 fps with the 329 and it is still moving 1540 at 1000 yards.
My 2 cents worth - the .375 will be perfectly adequate for the game you have in mind. Another option is the .400 H&H magnum of 2003 which uses a necked up .375 case. From an article on this caliber in the NRA American Rifleman "With so many good choices available I’m not certain another cartridge in this power range is an absolute necessity, but the .400 H&H Mag. is definitely a good one, and I suppose there’s always room for one more. Offering smooth feeding and relatively mild recoil, the .400 H&H Mag. is well worth considering—especially if you’re looking for a big bore that’s a bit different."
well, here ya go...
don't get hung up too much on foot pounds, they don't kill stuff. great bullets thru vitals kill stuff. the 416 will certainly hit harder, you and the target. the 416 ruger is pretty versatile too, especially if you use lighter bullets (350 gr) 
Big bore addiction, yeap. My friend (the Smith thats doing it) keeps telling me that I need a .600 Overkill. 725 grains at 2800 fps lolwell, here ya go...
I have a 375 ruger, stainless, 20" barrel, houge stock. it is a great rifle, will for sure do anything you need, but...you already know this.
that is a pretty long barrel, wont even go in my gun safe well!
ultimately, you need to decide. you have asked the right group of enablers the question, what do i do??
my 2cents, shorten the barrel and keep the 375 ruger. a little less velocity will not be noticed by anything you shoot well, and....you are not shooting ground squirrels at 500 yards with it. if you think there is something it wont do for you, (there really isn't) then buy a bigger gun. be careful tho, the big bore rifle addiction is also something this group can speak to!
let us know what you decide.
