I got my first .375 in the late 80's. Since then I have had four or five different rifles, all having worked hard. A couple were sold when all that was salvageable were maybe the open sights and the triggers. When I was guiding buffalo hunters in Arnhemland, Northern Australia, both loan guns were chambered in .375 and I witnessed clients take over 40 buffalo and numerous Scrub bulls with those rifles. When not physically guiding hunters, in between hunts, at the beginning of my season, and at the very end, I kept a entire community of some 200 people constantly fed with protein taken from Scrub bulls hunted whilst on my own in very remote locations with no back-up and no safety net. Most of the scrub bulls I took over a ten year period, averaging 15 - 20 or more per year, were taken with a .375 I also took numerous sick, injured and cull buff at the end of each season, again on my own with no back-up, comfortably with very few "incidents" with a .375. Ironically, today there is no .375 in my cabinet, the first time in over thirty years but in my humble opinion the .375 remains as one of, if not THE, most useful, versatile and effective medium to large game calibre ever to be designed. Not my first choice for dedicated buff hunting and definitely not my first choice for backing up clients, but none-the-less a stunning performer when used appropriately.