I used my Ruger 77 .338 Win Mag on my first plains game hunt. Using Winchester factory 230 grain Fail Safe ammo, it shot through most critters, including Eland with one exception; that was a bull Gemsbock shoulder shot at 150 yards. The bullet shot through both shoulder bones, breaking the back for a bang - flop! The bullet was recovered under the off side skin and had an oval cross section! A tough bullet for a tough critter! I keep that bullet on the shelf in front of this computer as a reminder of a great hunt. Given the opportunity, I would surely use that bullet -rifle combo on a buffalo. It shoots every weight bullet from 210 to 250 well.