I am aware that the legal minimum is 375 however, my question is more to the guys that have some experience and have shot one or a few buffalo. I plan to hunt with Ivory Trail safaris in the Save' valley in 2022. I'll be hunting buffalo and plains game. I plan to take my 458 Lott for buffalo and the 375 for plains game. I have watched a lot of buffalo videos and it appears that thier ability to soak up lead is not exaggerated. I do understand that you can kill one with a 375, however I feel that seems the same as saying you can kill and Elk with a 270. Yes you can but does that make it an elk rifle? In my opinion no. I have always been a fan of bringing plenty of gun. 338 lapua is pretty much my go to hunting rifle for most things. I chose the 375 over it for plains game because my 338 is a tactical type rifle and I just don't think it fits on a safari. Kind of like playing an electric guitar in an orchestra. So back to the point, if someone says hey lets go hunt a buffalo, what cartridge pops into your mind as the minimum that you want in your hands when you are standing 40yds from a buffalo?