Hi Cal,
Welcome back to the big bore lever gun!
My 1886 and 1895 Winchesters have done well in Africa and if you do begin preparation for such a Safari, I can share some Safari Proven .405 and .45-90 load data with you.
I still remember showing the 400 grain .405 cartridge to a landowner to convince him my 1895 levergun could handle a Cape Buff. After the hunt, he provide refreshments and wanted to chat about the rifle and the hunt.
I think he was convinced of the effectiveness of the cartridge, especially with modern bullets. He had seen the 1+ inch hole in the heart left by the Woodleigh Weldcore that entered behind the rearmost rib and exited between the front legs (just where the PH told me to shoot).