Yep, I am aware of Roy killing a buff with a behind the shoulder double-lung shot once with it, but he reportedly admitted freely that it was just to verify that it could be done, and he did not recommend it. No kidding !?!!? LOLPascal, I don't know if you know this or not, but Roy Weatherby shot a bunch of game to include a Cape Buff with a 257 Wby. This was done way before we had the quality of the bullets we currently have. I've only killed deer & hogs with my 257, and it kills like the hammer of Thor. I have several friends who hunt Elk, and they use 270, 25-06 & 30-06 successfully every year. IMO, shot placement is the key here.
Shot placement Amen! But sometimes one catches the shoulder instead of slipping between two ribs just behind it, and this is why I will limit myself to the smaller stuff with the .257. My big bone crusher will remain the .340 ;-)