Looks like .375 is the go. Ive only shot one and enjoyed it. I havent any big game experience but i know its the minimum DG cal in most places.
I bought a new.458win mag on clearance but feel the .375 H&H is a classic and would be all o need when i do travel.
Bigger is better, until you can’t handle it instinctively.
For me, a warm, but not hot .375 load is that sweet spot between power and handling.
Yes, I can shoot heavier calibers, second shot accuracy and time suffer greatly though.
Give me a few more years, and another 1k of .375 practice, and I will probably pick up a .416
I have never been in a situation where my .375 felt lacking though.
P.s. fully aware that if someone does find themselves in a situation where they need a .416 over a .375, they may not survive to learn.