I drew my first Moose tag in 6 years this year, 260 gr Accubond will get the job done. I’ve had really good luck with the Accubond over the last few years.
did not expect such good bullet performance at that range from a lowly cup and core bullet in "cheap" factory ammo. The .375 works well on moose sized game. Don't over think things.
My current battery consists of a .270 and a .375 I don't feel the .270 is adaquite for moose sized game.
One more comment about scopes - The second most recent moose I have killed, previous to the one in the picture I posted, was shot with my Brno 22F 7x57 topped with a Leupold 2.5x scope. Range was 250 long steps. Norma 170 gr. RN factory load, almost antique ammo. I did not find scope ( or cartridge) to be a handicap. It's more about how you shoot, not what you shoot 'em with.