I have contemplated the same thing. If I were to take 1 rifle for PG and a Buff - what would it be and I have decided it would be my .375. But I have just the opposite thought pattern. With having invested in a Dakota 76 African in .416 Rigby, a Heym Martini in .404 Jeffery, the new MRC Tsavo in .375, and a Rigby Highland Stalker in .275 Rigby - I want to take them all! I have decided my next Africa trip I will use the 416 Rigby on my buff, and the Rigby HS for plains game. The next rip will be my .404 Jeff for a croc. and the Tsavo 375 for PG. I got to get them all in!