While I have not used the 404 400gr TSX bullet on buffalo, I have used the 375 300gr TSX on 4 buffalo. In my experience when I was running them at 2450 fps when I hunted Australia water buffalo, they killed very well. However on some of the shots that weren't within 50 yards or less, I noticed the bullets didn't expand nearly as well. So by that, I would say to keep your muzzle velocity up as high as you can stand it, or just use a Swift AF.OK, can I ask you guys who have actually shot a buffalo with this bullet to comment on bullet performance? I’m interested in range of the shot, response of the animal to the shot, as well as penetration/expansion details.
82 grains RL17 at 2325 FPS. Shot was quartering towards 75 yards. Spinal shot to cervical/thoracic junction. Dropped to shot. 8 inches of vertebral bone destroyed. Insurance paid with Barnes solid 75 grains RL17 same velocity/point of impact.I am heading to Limpopo in May for buffalo, and would like to load the .404 Jeff, 400 grain TSX. What velocity will give me optimal bullet performance?