I have been on 15 hunts in Africa, most for dangerous game. I am still a novice as compared to most and especially to the PH's and local hunters.
I ask them about the 45-70, 45-90 and whatever - they all laugh and say, "If you want an early funeral, use that". I get even a more emphatic response on bow hunters wanting to take on buffalo or lion or ele. They say, "Yep, it will kill a lion or buff or ele, but not before they kill you".
This topic comes up regularly by someone wanting to prove a point about an out dated and under powered cartridge. Let me put it this way - if you need an operation, would you have a doctor cover you face with an ether soaked cloth then cut you open with old scissors or knife like in WWI or other eras? Why in the world would anyone think hunting dangerous game with less than adequate tools is a good idea?
You become a Darwin Award candidate when you do this......