Speer 150 grain hotcore in .308 is lights out for my 30-06. They smack the white tails here with more authority than anything else I have tried. And they fragment, a lot, but not until getting to the vitals. It’s like...magic.... Punch right through a rib, go in 2 more inches.. and... hand grenade. Hit the front leg bone, 2-3 more inches... hand grenade. Front shot, little high, never reaches the spine, but the front of the neck looks like a grizzly took a bite out.... I can’t explain how the bullets know what to do, but with over 40 whitailes down with them, no losses. I had to track one about 70 yards. By track, I mean follow the Texas chainsaw massacre bloodtrail.