FWIW, the vast majority of international hunts my wife and I do are just 1 week in length.. With our jobs, kids, etc.. its not often that we can spend more than that gone at a time..
The way we do it is this..
We leave the US on a Friday afternoon (get a partial work day in on Friday).. that gets us to South Africa in the very early AM on Sunday (we usually take the Qatar flights out of DFW that land in Joberg in the oh shit its early in the morning on Sunday)..
We then have Monday through Friday to hunt (5 full days).. Fly home on Saturday.. which gets us back to Dallas on Sunday around mid day.. So we're gone 9 days.. but only have to take 1 week off of work since 4 of those days fall on the weekend..
The first couple of days on the ground jet lag can get to you a bit.. but I very purposefully put myself down hard on the flights going over and I very intentionally put myself to bed early on the first night of arrival.. so its really not all that bad..
Most of the time between the two of us we'll take 5-6 animals.. there's definitely no guarantee on an animal per day.. sometimes we're not as fortunate.. but most of the time 1 quality animal per day isn't too hard to accomplish for more common PG (kudu, impala, blesbok, blue wildebeest, springbok, zebra, etc..etc..).. if you're going to chase more complicated animals it might be better to plan for 1 animal every 1.5 or every 2 days.. and just have a shorter list..
If you're on a tighter schedule (like a 1 week hunt) I'd definitely recommend looking hard at outfitters that are close to Jo'berg or Cape Town.. that's not a hit on the guys at the far northern end of Limpopo or elsewhere.. that's just saying the last thing you want if you're on a tight schedule is to clear the airport and then spend another 4-6 hours driving to get to your location (thereby losing yet another day of time between the trip in and the trip out)..
There are plenty of outfitters within a 90 minute drive of OR Tambo that can have you hunting on the day of your arrival if you come in before noon (
@Bos en Dal SAFARIS is one of them

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