I second everyone that says one load. You will for sure have the wrong load in the gun at some point.
I set up with 300g TSX for my 375 when I thought I would need it for my buffalo hunt (managed to break the stock on my 404 at the last minute and purchased a 375 just in case). Did not end up needing the 375 for the buffalo hunt and took it on a plains game hunt the next year. The 300g TSX is just fine for plains game.
The 270g LRX does sound like it would be fun to play with and no doubt it would work well on plains game. Probably work fine on buffalo as well, but there is clearly no need for the better BC on a buffalo hunt, so why not use the 300? If I were going on a plains game hunt somewhere that I thought I could benefit from the better trajectory of the LRX 270, that is all I'd be bringing.
I set up with 300g TSX for my 375 when I thought I would need it for my buffalo hunt (managed to break the stock on my 404 at the last minute and purchased a 375 just in case). Did not end up needing the 375 for the buffalo hunt and took it on a plains game hunt the next year. The 300g TSX is just fine for plains game.
The 270g LRX does sound like it would be fun to play with and no doubt it would work well on plains game. Probably work fine on buffalo as well, but there is clearly no need for the better BC on a buffalo hunt, so why not use the 300? If I were going on a plains game hunt somewhere that I thought I could benefit from the better trajectory of the LRX 270, that is all I'd be bringing.