The 375 is not generally intended as a long range gun. I have the Ruger Hawkeye Alaskan in 375 Ruger. I have always had rifles with 24-28 inch barrels and shoot a lot at long range. I really fell in love with the Alaskan. It is very accurate (sub MOA) and I am using loads with 300 gr bullets that are getting an honest 2600 fps out of the 20" barrel. Is very handy to carry and shoot - I actually think I have missed the boat the advantage of the short barrell for the last 40 years. I have spent way too much chasing another 100 fps and not being practical. Actually the shorter barrels are stiffer and this aids the accuracy. I feel as comfortable with this gun out to 300 yards as I do with the long range guns at 500 yards plus. For intended use of 300 yards and in I don't think you are sacrificing anything with the 20" barrell. I chose this gun over my others for Brown Bear in Alaska in May. I am also a fan of synthetic stocks hunting purposes and really like the feel of the Hogue stock on the Alaskan.