I hunt almost exclusively with handguns.
Energy=mass x velocity, and handguns don't have velocity. Handgun and rifle ballistics just are not the same game. Things like the 460 too much of a good thing IMHO, and in a crazy heavy frame. What is the point? You don't keep velocity with a .45 caliber flatnose flatbase bullet.
I find a 475 Linebaugh has more of a push recoil than a snap like a 454/460. I use solids exclusively, because who needs a jacketed bullet to expand? The diameter of the solid is already more than many softs expand to. I tried XTPs, and they fail on anything hard. Solids penetrate for days, and do the job every time.
I've had success on Cape Buffalo, giraffe, bears, moose and the like with a 5.5" barrel with iron sights. And the gun weighs around 44oz vs 94oz for a S&W. It is practical and carry-able, and doesn't need a brake to be shootable. I'm not sure what else you would want.
Pachmyar grips are awful. Bisley grips roll in the hand just right, and are far easier to manage recoil with. Rubber just grips you hands and torques your wrist. Ruger Bisley, Linebaugh conversions, and FA revolvers use them for a reason. Even with stout loads in lighter revolvers, they are very shootable.
FA97s are a smaller frame than the 83s.
I don't get the point to having a rifle barrel on a pistol. Buy a 4 3/4 lb rifle if your going to use a barrel that goes down to your knees. Handgun accuracy is a very perishable skill. The idea that a 7.5" barrel sight radius over 5-6" will make up for this is crazy. It takes a ton of practice, more practice, and then not forgetting to practice after the season is over and the next one is about to start.