I'll be the contrarian here - at least with regard to the Ruger package. The cartridge is fine - how could it not be when essentially duplicating the H&H - but I truly loathed the rifle. I purchased one very early on so it had the sling stud. Ergonomics, at least for me, were just wrong. The problem was drop rather than LOP (which can be easily fixed). The same high comb issue made using the open sights instinctively very difficult without bruising one's cheek. Add to that a rifle that was too light for the recoil it was generating. The stock looked like a stained 2x4 and the recoil crossbolts looked like a couple of random wood screws. After the second trip to the range, I could not get rid of it quickly enough. I have been using the H&H ever since to include with my R8. Though the Ruger cartridge itself would be fine in the right rifle.
Just as a word of caution. Mitigating the recoil issues with the Ruger by using a muzzle brake is a bad idea if you plan to actually hunt the rifle in Africa. Brakes are truly loathed by professional hunters because of the lateral noise and blast effect. These guys depend on their ears as much as their eyes, particularly when trailing elephant of buffalo. He won't say anything to your face, but picking up tinnitus while chasing zebra will not endear him to you.