It's not. The 416RM barrel is a 22mm Selous profile, and that's not optional if you go with a Blaser factory barrel. The 375H&H I'm shooting has a 17mm standard profile barrel. It all depends how you set yours up. My 416RM was as heavy as I could get it, where the 375H&H is as light as I can get it.
The 416RM weighed over 13 lbs with the scope, sling and 4 cartridges. It had the steel receiver, steel trigger group and kickstop that come with the PH model. To carry this rifle in the field was more like dragging a club than toting sporting arm. I decided for the number of times I'm likely to hunt DG, I'll do so with a 375H&H that's easy to carry and shoot.
EDIT - I hesitated at loading a third cartridge because the first one knocked one of the chains off the steel target. The second shot, I hit the swinging target and knocked the other chain off. If you slow down the video, you can see how close I come to getting scoped. I never did, but it was always a concern.
SHOOTING-SOFT LLC shooting simulators might offer a useful way to practice without recoil. Also taking into consideration that I'm recovering from arthroscopic shoulder surgery, a .400+ cartridge is not likely in my future.