@Nevada MikeThe number of wildcat cartridges that are now 'factory' rounds is long and distinguished...
and a bunch more.
I own a Ruger No.1 in 25-'06 (25" barrel) and a .257 Roberts. I like them both! the .257 is a 300 yard rifle, but the .25-'06 is great for those loooong shots on Coues deer and antelope. The 25s work well on coyotes, too.
You've got to love the 25s for versatility.
The 25 out six and the 257 Weatherby and my own 25/303 Epps Newton improved are even more of a good thing