While I can generally tie my own shoes, sometimes a bit stiff trying to do so mid-sheep hunt. I really only use the safety in Africa since I also do not carry a chambered rifle. On sheep hunts I chamber when ready to shoot, moose and bear, maybe as I start a final stalk and then engage the safety. I do not prefer the older flag style safety though, mostly because of big thumbs and modern optics simply do not allow appropriate room to articulate without pinching or smacking my thumb into some part of glass or gun. I think they are classic cool, and do have them on a couple or iron sighted Mausers, and have one Holland and Holland with the side rocker safety...much prefer the three position safety of the three...but its what I grew up using since a young child, so its overly familiar.
For a new build or new trigger, go with what you know and prefer. As long as you are comfortable and proficient with it, I think they all work as designed. If you pack a rifle through tight trails, especially if choked out with willow or alder, I will say the bolt lock is nice...or just turn it bolt in against the pack as I do in those tight areas.