A word of caution, Double Rifles are very addicting.  I've owned several brands.  Have 3 Heym's and a
Chapuis (and just purchased my 2nd).  I really like V-C round bodies but have never found one that is
even close to fitting me and with the status of the company won't even try to order one.
The 450-400 is a dream to shoot, my Heym 470 is brutal and significantly more uncomfortable than
the 500NE I have (all in how the stock fits).  I'm glad that there are some who like the S2, Altitude Sickness's dog is better looking than a S2.
I was very tempted to buy Marks 500-416 recently but after 40 years of Surgery, the cocking mechanism doesn't work with my arthritic right thumb.  Its a splendid caliber.  My current quest is
a 450 #2 which is one of the best DR calibers ever,  too bad none of the manufactures have an
interest in building one.  They also have no interest in the 450 3.25