Taken from a post on another forum. I don't think this gentleman is on this forum. He is a rather humble fellow with quite a bit of African game shooting experience.
"I have taken 19 buffalo with the 375 H&H. One with 300 Swift AF’s (3shots). Six with 250TTSX (one shot each). Five with 270LRX...
I have a couple of boxes of the 300 TSX. I bought them during the oboma shortage years. At the time, I could not find the 350 TSX in stock. I know of a few folks that have used the 300 grain in various 416's for moose and bear.
I have stuck with the 350 TSX, recently the 350 TTSX, and currently...
I don't have a Taylor, but do have 416 Rugers and Remingtons. Several very good 416 bullets, and in my opinion the 350 TSX is definitely one of them. I would also look at the 325 grain CEB Maximus and Hammer Stone Hammer. Hammer and Barnes also offer 300 grain versions. Also the 350 Swift...
Here are the pictures from @50Gunner:
The grumpy Buffalo carrying the .416 bullet for 6 months. The 458 Winchester rifle and a loaded round with the 404 Stone Hammer.
The internal ribs, exit side of the .458 404 Stone Hammer.
The shank of the .416 400 grain Maximus that the old boy was...
Long ago, I bought an Interarms 375 H&H that Bubba slicked up tooling marks on the bolt face. The firing pin hole was dished out / concave enough that it would pierce primers. Carried it to gunsmith that modified a lot Mark X / Whitworths, he happened to have a space bolt that head-spaced and...
I am content with my / Barnes' H380 load for the 270 grain TSX and LRX. Good to have options though.
I do use the 2000-MR in the 416 Ruger and have some 416 Remington loaded with it. It seems to do very well with the 350 TTSX.
A big thanks to George Hoffman for the development of the 416 Hoffman. And, Jack Carter for bullet development progress.
I met one bear guide that absolutely loved the 400 grain TBBC Federal factory loads on the big bears.
The TBBC component bullets are difficult to find most of the time...
Federal's 416 Ruger, Remington, and Rigby load data for the 400 grain TBBC.
https://www.federalpremium.com/on/demandware.static/-/Library-Sites-VistaFederalSharedLibrary/default/dw6af4cbb7/productPdfFiles/PB416TBBC400_Reloading_Data.pdf
The 250 grain TBBC.
https://www.federalpremium.com/on/demandware.static/-/Library-Sites-VistaFederalSharedLibrary/default/dwdf1dd25f/productPdfFiles/PB375TBBC250_Reloading_Data.pdf
Federal's load data for the 300 grain TBBC in the 375 H&H, Ruger, and RUM cartridges.
https://www.federalpremium.com/on/demandware.static/-/Library-Sites-VistaFederalSharedLibrary/default/dw195f18c1/productPdfFiles/PB375TBBC300_Reloading_Data.pdf
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