My only experience is with the.375 Whelen (not Improved). 300 gr aframes took everything from wildebeest and zebra (400+yds) to eland and sable at over 200. 300 gr @ around 2400 fps.
Well, I just returned from a duck hunt in the sloppy south Louisiana salt marsh.... I carried a 95 yo AH Fox AE grade 16 bore. I bought it to use it. It does little for me reposing in my safe in luxury. She's a working girl!
This is WAG, but I would figure that you would lose around 25-30 fps per inch of barrel lost. The larger the bore, the less the velocity lost per inch of barrel cut. YMMV
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