Gents, Just to add another perspective to this thread, which I feel is somewhat connected to the arguments here. We all agree that premium bullet + shot to the vital area will get you your animal. I think a very important factor that can be added here when hunting African game is to know where the vital area is on your intended target. I know this sounds like something obvious, but it is probably the single most factor for animals not going down immediately. Not necessarily a bad shot, but an incorrectly placed shot. Some animals might carry a hump on the back, like the Blue Wildebeest, which distorts the hunter's judgement of the animals centreline, causing the shot to be placed too high. (...giving the impression that they are bullet proof) Gents, do the research on your animals before your trip. An excellent source of info would be the shot placement gallery of AH, or Dr. Kevin Robertson's "The perfect shot" pocket guide. I carry one for my clients to keep with them for the duration of their trip. Know your gun and its capabilities and research your quarry.