COVID-19 Coronavirus UPDATES, BANS, CLOSURES, ADVISORY, etc.

[cpr0312]

 

[lwaters]

Sure seems the world is bent on economic self destruction.

I wonder if there is a lot of poaching going on

 

[Tanks]

Tanzania is NOT looking good. @Bullet Safaris have you seen this?

https://www.cnn.com/2020/05/13/africa/tanzania-coronavirus-us-embassy/index.html

 

[BRICKBURN]

 

[SafariA]

Maybe we can give this midget opportunity at some range training ...

 

[Tanks]

At that distance, with a shotgun, all he has to do is point and shoot.

 

[Ironhorse375]

I've followed this thread for awhile.
Its been tempting to jump in and give some first hand perspective.
I'm in a unique position to now attempt to engage this subject.
First of all what we absolutely know today about treatments, methodology and survivability could very well change in coming days or weeks.
40 years in medicine have taught me the only constant in Healthcare there is always change.
10 years as an EMT and paramedic followed by 29 years as a nurse in both ER and ICU at a level 1 trauma center there have been challenges. The Aids HIV epidemic, H1N1, ebolla, Sars have been killers.
Covid 19 has presented a host of issues
Medical, financial, social.
In the ICU, we have 5 in our hospital 12 beds each. We ran short of PPE, ran out of ventalators one day, and saw patients die.
Our treatment with several different medications and advanced modes of ventilator settings seemed to work for some but not all. Policy and procedures would change mid shift at times.
Some evidence anecdotal suggests we are putting patients on ventilators to soon.
Now we see there are micro thrombosis, " small blood clots that are a newer concept and concern leading to stroke/ brain injury in some along with multi organ failure with this disease that mimic other disease patterns that complicate treatment modalities even further.
Good news is not everyone with COVID-19 becomes critical. Many have mild symptoms and seem to do well.
Those with prior lung issues or health " chronic issues" are more likely to suffer more.
I contracted COVID-19 most likely exposed at work in the ICU.
I was fortunate not to end up on a ventilator and am at home. But it knocked me down hard. And oxygen saturation levels are in 80s at times.
But ill recover and possibly have some immunity, time will tell.
Last time at work we were backed up over 600 surgery cases, some of those folks may suffer more as the elective surgery now may become urgent or emergent as their before treatable symptoms now become more complex.
The man that doesn't get a clonoscopy that was scheduled might have had a undiagnosed cancer that would have been extremely treatable now is stage 4 and he may die.
I can say it's time to open the economy up. People need to have a sense of purpose and financial stability. We are not going to print money fast enough to make it work.
Some folks have jobs that are in my opinion as essential as mine.
Keeping the markets stocked, the roadways functioning, manufacturing, ranching, teachers, everyone is essential in one way or another.
Maybe some politicians are an exception here.
As a country and as society we can't live in fear of the " what iffs" the maybe ill hide in a bubble "
I'm not naive, but when I'm cleared to go back to work I'll be there. And I'm glad to have that opportunity.
Precautions sure, especially for the most vulnerable and a good dose of common sense go a long way.
But undoubtedly human beings will have to move forward in this world.
Stagnation and the curtailment of our lives and liberty are not the answer by a long shot

 

[cpr0312]

 

[Nyati]

@Ironhorse375 , you have just pointed out something nobody wants to speak about. The aftereffects of the virus in people like yourself which have successfully been through it.

Some are just fine, but others are suffering some ailment or another, and some are back in hospital with blood clots.

No, its not just a flu, like I´ve often read.

Wish you a total and speedy recovery

 

[VonJager]

The virus is here......if you keep the lockdown for another 10 days.... 10 weeks... 10 months the virus is still going to be here.... And unfortunately after lock down is lifted cases will rise as the virus is still here.....as the Swedish government adviser says in the interview with Australian tv....great new Zealand has got no new cases and Australia is down to small amount... so are you going to keep your borders shut for the next 30 years as that's what you will have to do to keep it out.... As its here......so catch 22.....no win situation.... But the businesses and economies have to start pumping again fast or there won't be any left......then let's see the chaos that will occur worldwide...... Unfortunately it's here....it's been let out of the bat.......

it's been let out of the lab.

FTFY

 

[BRICKBURN]

Maybe we can give this midget opportunity at some range training ...

I'd suggest that the runt uses the proper eye if they choose to shoot right handed.

 

[BRICKBURN]

At that distance, with a shotgun, all he has to do is point and shoot.

The reality is the muppet will also tear their own nose off the way it is mounted.
Should make them readily identifiable though.

 

[Wheels]

View attachment 347994

My first thought is we are about to see a black eye, but then...........

 

[Tanks]

The reality is the muppet will also tear their own nose off the way it is mounted.
Should make them readily identifiable though.

I think it will kick straight back rather than up though

 

[Ironhorse375]

@Ironhorse375 , you have just pointed out something nobody wants to speak about. The aftereffects of the virus in people like yourself which have successfully been through it.

Some are just fine, but others are suffering some ailment or another, and some are back in hospital with blood clots.

No, its not just a flu, like I´ve often read.

Wish you a total and speedy recovery

Thanks,
Its a bear for sure but survivable.
Working on getting endurance and lungs back into shape.

 

[spike.t]

Interesting article by Rocco forte the international hotelier.....rational logic

https://www.dailymail.co.uk/debate/...ites-hotel-chain-magnate-SIR-ROCCO-FORTE.html

 

[375 Ruger Fan]

Sorrento finds a coronavirus antibody that blocks viral infection 100% in preclinical lab experiments

Darrell Etherington
,
TechCrunch•May 15, 2020
https://finance.yahoo.com/news/sorrento-finds-coronavirus-antibody-blocks-130034416.html

Therapeutics company Sorrento has made what it believes could be a breakthrough in potential treatment of SARS-CoV-2, the virus that leads to COVID-19. The company released details of its preclinical research on Friday, announcing that it has found an antibody that provides "100% inhibition of SARS-CoV-2 virus infection of healthy cells after four days incubation." The results are from a preclinical study that still has to undergo peer review. It was an in vitro laboratory study (meaning not in an actual human being), but it's still a promising development as the company continues to work on production of an antibody "cocktail" that could provide protection against SARS-CoV-2 even in case of mutations in the virus.

Sorrento says it believes this antibody, which is labelled STI-1499, stood out among billions of candidates it has been screening from its extensive human antibody library for its ability to completely block the interaction of the SARS-CoV-2's spike protein with a human cell target receptor. That means it prevents the virus from attaching to the host's healthy cell, which is what leads to incubation and infection.

The nature of the antibody's efficacy means that Sorrento currently believes it will be the first antibody to be included in the cocktail it is developing, which will be made up of a large number of different antibodies that show efficacy in blocking the attachment of the spike protein, in order to provide multiple avenues of protection that are designed to remain effective even if the virus mutates in transmission from person to person, or within the same individual. One of the big outstanding questions that researchers are working on answering currently is just how mutagenic SARS-CoV-2 actually is, as many coronaviruses like the common cold show a tendency to mutate pretty quickly, rendering long-lasting cures and treatments difficult to develop.

Sorrento's COVID-SHIELD is meant to address this through a potent mix of different antibodies that provide protection against different strains of the virus, but the company says it also will be pursuing development of the STI-1499 antibody on its own as a dedicated, standalone therapy. The company is already in discussion with regulators about how to expedite development of that potential treatment, and is ramping its production capacity as well with the goal of producing as many as one million doses at the same time it pursues FDA approval for its use.

It's definitely worth cautioning that no treatment or vaccine is likely to be a "magic bullet" in treating SARS-CoV-2 or COVID-19, but this is still a promising development, and one to watch as it undergoes clinical trials and the therapeutic development and regulatory process.

 

[spike.t]

Sorrento finds a coronavirus antibody that blocks viral infection 100% in preclinical lab experiments

Darrell Etherington
,
TechCrunch•May 15, 2020
https://finance.yahoo.com/news/sorrento-finds-coronavirus-antibody-blocks-130034416.html

Therapeutics company Sorrento has made what it believes could be a breakthrough in potential treatment of SARS-CoV-2, the virus that leads to COVID-19. The company released details of its preclinical research on Friday, announcing that it has found an antibody that provides "100% inhibition of SARS-CoV-2 virus infection of healthy cells after four days incubation." The results are from a preclinical study that still has to undergo peer review. It was an in vitro laboratory study (meaning not in an actual human being), but it's still a promising development as the company continues to work on production of an antibody "cocktail" that could provide protection against SARS-CoV-2 even in case of mutations in the virus.

Sorrento says it believes this antibody, which is labelled STI-1499, stood out among billions of candidates it has been screening from its extensive human antibody library for its ability to completely block the interaction of the SARS-CoV-2's spike protein with a human cell target receptor. That means it prevents the virus from attaching to the host's healthy cell, which is what leads to incubation and infection.

The nature of the antibody's efficacy means that Sorrento currently believes it will be the first antibody to be included in the cocktail it is developing, which will be made up of a large number of different antibodies that show efficacy in blocking the attachment of the spike protein, in order to provide multiple avenues of protection that are designed to remain effective even if the virus mutates in transmission from person to person, or within the same individual. One of the big outstanding questions that researchers are working on answering currently is just how mutagenic SARS-CoV-2 actually is, as many coronaviruses like the common cold show a tendency to mutate pretty quickly, rendering long-lasting cures and treatments difficult to develop.

Sorrento's COVID-SHIELD is meant to address this through a potent mix of different antibodies that provide protection against different strains of the virus, but the company says it also will be pursuing development of the STI-1499 antibody on its own as a dedicated, standalone therapy. The company is already in discussion with regulators about how to expedite development of that potential treatment, and is ramping its production capacity as well with the goal of producing as many as one million doses at the same time it pursues FDA approval for its use.

It's definitely worth cautioning that no treatment or vaccine is likely to be a "magic bullet" in treating SARS-CoV-2 or COVID-19, but this is still a promising development, and one to watch as it undergoes clinical trials and the therapeutic development and regulatory process.

Sounds like an announcement to get their shares ramping up....too many buts and ifs....not apologising for being cynical...but people have to get used to the fact it's here.....same as the other sars...including the sort of normal every day ones like .flu .. cold..etc...etc....viruses....and they haven't come up with anything magic for those yet....

 

[375 Ruger Fan]

Namibia bans car perks for politicians for virus spending
News24
15th May 2020, 04:42 GMT+10


Namibia's president on Thursday slapped a five-year ban on buying new cars for top politicians and government officials in order to channel funds into fighting coronavirus, his office said.

President Hage Geingob "has directed that the vehicle fleet of the Namibian government will not be renewed for the period 2020-2025," presidential spokesperson Alfredo Hengari announced in a statement.

"No new vehicles will be purchased for members of the executive and public office bearers in the Namibian government."

He said the decision would save some 200 million Namibian dollars ($10.7 million), which will be directed "to urgent priorities, specifically at a time when the country is dealing with the health and economic implications of Covid-19".

The southern African country of 2.5 million people has so far recorded 16 cases of Covid-19, with no deaths.

Namibian ministers and their deputies each qualify for Mercedes-Benz vehicles upon their appointment.

The president also directed a limit on monthly fuel consumption for top politicians, the government said.

In 2002, then-president Sam Nujoma had banned the use of Mercedes-Benzes, insisting that ministers should ride in Toyota Camry cars.

 

[Wheels]