2150fps is about ideal for the Woodleigh RNSP to perform as it was designed.
If you decide to go that route I doubt you will have too many complaints, personally though i'm not sure i'd want to down-throttle my own Lott to that.
My personal load in my Lotts, which incidently weighed 8.5lbs field ready, was a 500gn at 2250. At this velocity the Woodleigh will still perform adequately for most "normal" hunting situations were the initial shot is taken at 50 - 100yds.
The only circumstances I was a little disappointed with the Woodlieghs were in "stopping" situations were the shot being taken was at less than 15 yds and the projectile is at full velocity.
As a client hunter, and not the PH, you can cover all bases by loading the Wooldieghs at 2200 for the first shot, it is unlikely you will need to take a first shot at less than that distance and then fill the magazine with solids for going away shots and any potential charge stopping situation.
If you decide to go that way then load a GOOD solid; i.e LARGE frontal meplat.
Good hunting.