I have a 6.5 PRC and after testing it on numerous whitetail and coyotes I am considering taking it to Africa. I will do more hunting with it before I decide for sure as it is a much smaller caliber than I normally take. I will not be hunting much of anything bigger than an Nyala so don’t jump on me about taking a smaller gun!
You can not worry about ammo availability in Africa. This is of the most discussed topics on AH yet the least likely to happen. It has never happened to me and I’ve been to Africa 15 times. Take whatever rifle and caliber you like and go hunt! If things go sideways you can always borrow an excellent gun for your safari.
Regards,
Philip