I own and shoot a .460 Weatherby, which I do quite often at our local range with no reduced loads, shooting various 500gr bullets (with and without the Weatherby muzzle brake).
I have had the pleasure of Pierre van der Walt's company on a few occasions, prior to his departure for Portugal, discussing the .460 and the .378 Weatherby (which I also own and shoot as often as I can)...
I have read the section in Pierre's book, "African Dangerous Game Cartridges" - CHARACTERISTICS of the .460 more times that I can remember. Especially his comments about what has been perpetrated about the .460's recoil
a very definite and good read.
Few will admit or acknowledge that the .460 generates nearly 12% less recoil than the .500 Jeffrey, so says Pierre in the same section.
That said, I will be testing a new batch of the Peregrine 500gr - VRG3's as soon as these current Covid restrictions are lifted and hope to get up to 2500fps.