I know this is old but I'll jump in as I just found it. And it sounds like no one has used it on African game as of yet.
I personally use the eld X in my 300 win mag. I'm shooting the 212 with 71.5 grains of 7828.
I have shot 3 elk, and 2 Canadian moose with that set up. Moose being larger and thicker skinned then any PG I believe. All 5 of these animals died either in the same spot or went down within 50 yards. So because of this I felt like it would work just fine in Africa.
2018 when I went to RSA I shot a Sable, kudu, gemsbok, nyala, blue wildebeest, Impala, blesbok and zebra. And my PH made jokes about the lack of tracking required.
Yes it is a soft bullet designed for long range shooting. I had no shots in Africa under 125m. So the really close range I can't speak for. And yes the bullet does expand massively. But that massive expansion is basically a KE dump. Causing devastating damage inside. So if the bullet is placed correctly. You don't need a exit wound. As the internal damage is so bad. The organs will pool with blood so quickly the animal will lay with 50 yards of where you shot it. And that's on the long end. Almost everything I shot in Africa died within 10 yards. And for the guys afraid of bone shots. In Africa I admittedly was not worrying about meat damage. So I was shooting high shoulder on every animal. And it broke through everyone one of the above species shoulders.
As per the elk and moose I hunt locally. I tuck them behind the shoulder as I'm meat hunting and the same performance. Once I missed on a moose a little forward and actually smacking him right on the should blade. The moose ran like 30 yards and stopped as the internal damage was still so devastating. Broke the shoulder and still got deep enough in the organs with the KE dump. As he stood there wobbling I gave him a second just in case. And he fell immediately.
I think regardless of what bullet style you go with. Obviously other than varmint. As long as your making the right shots in the right spot then you shouldn't have a issue.