Have some similar data for you - used the .375 Ruger with Barnes TTSX 250 grain this past fall on a whitetail doe.
I was going to carry the 270s when I went this next month, until Chinese Flu wrecked the hunting world for 2020. Since I haven't been to Africa for hunting yet, will let those more qualified opine as to the .375 Ruger's suitability for African critters.
These show exit wound with hide.
