Bullet on the left is a 129 grain Hornady Inter Bond out of a 6.5 Creedmoor It will do almost anything a 308 will, with more range, much less recoil, flatter trajectory. Double the energy of a 243 at 500 yards. And better performance at all other ranges as well. But with very similar recoil. Take a serious look at a Ruger Hawkey Predator in 6.5 Creedmoor, the newer ones with the adjustable length of pull. Then spend some money on a good scope. I have a Swarofski 3.5-18x42 on mine with the ballistic turret. If you don't want to spend that much, look at a Ziess 3-15x42. They are on clearance. Or find a good used one. Keep the scope mounted low or get a cheek pad riser. I think Ruger has one on their web site. Make it fit her and she will be deadly with it. Lots of factory Ammo available now. If you do decide to use Hornady, for Africa I would (have used) use the 129 grain inter bond. Maybe the newer heavy for caliber long range stuff but i have not shot an animal with that yet. Federal also has out a new long range hunter line. Not that you need the range normally in Africa, just that the inter loc, sst, and target ammo is likely to be too soft for tough African game. And I've had bad results with GMX in larger calibers so I won't recommend that either.