I've been working up loads for my Ruger Hawkeye African 375 Ruger. So far, the most accurate loads have come with Barnes TSX bullets, both 270 gr. and 300 gr. My question is this- is it feasible to take just one load with the 270 gr. TSX, for buffalo and leopard? I can't think that 30 gr. of bullet weight is going to make a huge difference, especially since the 270 gr. is travelling faster. My plans are to hunt the leopard in northern SA, Limpopo province. I see conflicting info on minimum caliber for leopard. If lesser calibers are acceptable, I will take along my .300 Wby. If not, are there better bullets for leopard in the 375? My previous trips to Africa have been 'one weapon' events, and I kinda like the simplicity of one weapon, one load.