I've made two trips to South Africa, shot 15 animals, 12 different species, all but two were taken with 30.06 including blue wildebeest, black wildebeest and kudu. I lost one blue wildebeest due to no pass through of the bullet and thus no blood trail. It was a frontal shot I think was through one lung, didn't break the shoulder but we'll never know. That lost animal was $950. That is one good reason to shoot them through the shoulder to anchor them, don't worry about the meat. The bullets were all South Africa factory loads, 180 gr. The shooting was mostly 100-160 yards but there were three animals that were shot at 180+, 200, and 300 yards, all smaller antelope. Be knowledgable of the ballistics at 300 yards, you shouldn't be shooting further than that. My limited experience in hunting plains game is some of what others have said. Practice, practice, practice off of the sticks. I used photographic targets of plains game (you can get them from Safari Press) and practiced shooting at the desired spot on the animal. Seeing plains game in the scope was odd for me at the start. The first time I looked through my scope at a kudu it was like I was in a dream. I also used the targets for dry firing in my shop. One of the keys to shooting plains game, from my experience, is not shooting too high. No higher than 1/3 up from the belly line, right in the shoulder will save the animal suffering, or you having to waste time tracking it, and money if you don't find it. Your list of desired animals is great, you are going to have a life changing experience and loads of fun. I'm going to bet that the animal most difficult for you to take will be the warthog, at least is has been for me. I've yet to score on my warthog boar, came about a half of a second from planting one on the last trip but he took off running. One more suggestion, if your PH sees an animal not on your list and says "That is a really good (whatever), you need to take it." give that serious consideration. I didn't and missed out on a couple of beautiful trophies I wish I had now. You didn't say (or I missed it) where and when you're going. Keep posting your plans, ask questions, and be darn sure to post a report (WITH PHOTOS) when you get home. Stay downwind and shoot straight.