No animal, anywhere on any planet would know the diff between the two.
Not belted, holds a little more powder. So slightly better velocity, but other than that not much. Not running the cartridge down, just don't see a lot of upside in comparison to the H&H.
Merry Christmas to all Ho,Ho,Ho,
Welcome to AH.
How does the 375 Ruger differ from the 375 H&H?
What about a CZ 550 American Safari or a Sako AV?
I'd give Honeybadger's Ruger Alaskan a look. You sure won't find a .375 for less and that short barrel could come in handy should that cat take strong exception to you putting a hole in it!