What keeps you from taking your dream hunt to Africa because you are afraid of coming home empty handed?
For me it's the leopard! He's unpredictable, expensive, and I'm not thrilled about sitting in a blind waiting, hoping, and praying for Mr. Spots to show up.
In North America it is the Sonora Mule Deer. I would say stone sheep but he is crazy expensive. I'd love a big mule deer but tag soup would not taste well.
I didn't mention bongo, mt. nyala, or lord eland derby because they are very specialized hunts.